4-[(N-tert-ButoxycarbonylaMino)Methyl]aniline

4-[(N-tert-ButoxycarbonylaMino)Methyl]aniline - Names and Identifiers

Name	tert-butyl (4-aminobenzyl)carbamate
Synonyms	4-(N-BOC-AMINOMETHYL)ANILINE 4-[(N-tert-Butyloxycarbonyl)aMi tert-butyl 4-aminobenzylcarbamate tert-butyl (4-aminobenzyl)carbamate tert-Butyl (4-aminobenzyl)carbamate 4-[(N-tert-ButoxycarbonylaMino)Methyl]aniline [(4-AMinophenyl)Methyl]carbaMic Acid 1,1-DiMethylethyl Ester CarbaMic acid, [(4-aMinophenyl)Methyl]-, 1,1-diMethylethyl ester Carbamic acid, N-[(4-aminophenyl)methyl]-, 1,1-dimethylethyl ester
CAS	94838-55-8
EINECS	229-591-5
InChI	InChI=1/C12H18N2O2/c1-12(2,3)16-11(15)14-8-9-4-6-10(13)7-5-9/h4-7H,8,13H2,1-3H3,(H,14,15)

4-[(N-tert-ButoxycarbonylaMino)Methyl]aniline - Physico-chemical Properties

Molecular Formula	C12H18N2O2
Molar Mass	222.28
Density	1.095±0.06 g/cm3(Predicted)
Melting Point	75-78°C(lit.)
Boling Point	382.3±25.0 °C(Predicted)
Flash Point	185°C
Vapor Presure	4.78E-06mmHg at 25°C
Appearance	Crystalline Powder
Color	White to tan
pKa	12.62±0.46(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.542

4-[(N-tert-ButoxycarbonylaMino)Methyl]aniline - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29242990
Hazard Class	IRRITANT

4-[(N-tert-ButoxycarbonylaMino)Methyl]aniline - Introduction

tert-butyl (4-aminobenzyl)carbamate is an organic compound with the chemical formula C12H18N2O2. It is a colorless to slightly yellow solid, stable at room temperature. Here are some of the properties and uses of the compound:

Nature:
- tert-butyl (4-aminobenzyl)carbamate is an amino-protected compound, where BOC is an abbreviation for t-butylcarbamoyl. It protects the amine group by a Boc protecting group, making it more stable for selective reactions.
-The compound has high solubility in solvents and can be used as an intermediate in organic synthesis.
-It has good thermal stability and chemical stability, and can be used under a variety of reaction conditions.

Use:
- tert-butyl (4-aminobenzyl) is carbamate commonly used in organic synthesis. As a protective agent for amine groups, it can prevent unwanted reactions from occurring and is easy to remove at the same time, making selective reactions easier to achieve.
-It can also be used as an amino protection reagent and can be purified on cationic ion exchange resin.

Preparation Method:
- tert-butyl (4-aminobenzyl)carbamate can generally be obtained by reacting 4-aminobenzoic acid with t-butylcarbamic acid chloroformyl (BOC-chloroformyl).

Safety Information:
- tert-butyl (4-aminobenzyl)carbamate are general organic compounds and have certain irritation. Skin contact and inhalation should be avoided.
-Wear protective gloves, glasses, and lab coats when used to ensure that the operation is carried out in a well-ventilated laboratory.
-When storing and handling, please follow the relevant chemical safety procedures.

Last Update：2024-04-10 22:29:15